Loss of growth differentiation factor 9 causes an arrest of early folliculogenesis in zebrafish - a novel insight into its action mechanism
Weiting Chen, Yue Zhai, Bo Zhu, Kun Wu, Yuqin Fan, Xianqing Zhou, Lin Liu, Wei Ge
This study shows that loss of Gdf9 in zebrafish causes early follicle arrest and sex reversal, which can be rescued by inhibin mutation, suggesting Gdf9 acts via the activin-inhibin system.
PLoS Genetics · Dec 15, 2022Peer-reviewedDevelopmental Biology