Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis
Zhongfu Shen, Yang Lin, Jiajun Yang, David J. Jörg, Yuwei Peng, Xiuli Zhang, Yifan Xu, Luisirene Hernandez, Jian Ma, Benjamin D. Simons, Song‐Hai Shi
The paper quantifies the progenitor cell behavior and gliogenesis program in the mouse neocortex, revealing a 60%:15%:25% propensity for astrocytes, oligodendrocytes, and both, and links gliogenesis to tumor suppressor loss.
Cell Reports · Mar 1, 2021Peer-reviewedDevelopmental Biology