Pathological turret mutations in the cardiac sodium channel cause long-range pore disruption
Z. F. Habib, M. Kohli, S. C. Salvage, T. Rahman, C. L.-H. Huang, A. P. Jackson
The paper investigates how turret mutations in Nav1.5 disrupt the sodium channel's structure and function, affecting ion permeability and causing cardiopathologies.
bioRxiv · Jan 15, 2021 · PreprintBiochemistry