Comparative effects of oncogenic mutations G12C, G12V, G13D, and Q61H on local conformations and dynamics of K-Ras
S. Vatansever, B. Erman, Z. H. Gumus
This study compares the local conformational changes and dynamics of four K-Ras oncogenic mutants using molecular dynamics simulations to inform inhibitor development.
bioRxiv · Mar 26, 2020Biophysics