Reduced local mechanical stimuli in spaceflight diminishes osteocyte lacunar morphometry and spatial heterogeneity in mouse cortical bone
J. C. Coulombe, Z. K. Mullen, A. M. Wiens, L. E. Fisher, M. E. Lynch, L. S. Stodieck, V. L. Ferguson
This study shows that microgravity alters osteocyte lacunar shape and size in mouse cortical bone, with changes dependent on local mechanical loading and biological environment.
bioRxiv · Jan 4, 2022 · PreprintBioengineering