L. E. Fisher

High-frequency amplitude-modulated sinusoidal stimulation desynchronizes neural activity and enhances naturalness of evoked sensations

This paper introduces a new electrical stimulation waveform that evokes more naturalistic neural activity than traditional methods, as shown by human experiments and computational modeling.

Computational modeling of dorsal root ganglion stimulation using an Injectrode

The paper models the Injectrode system to determine how design parameters affect neural activation, finding that larger surface area reduces pain-related activation.

Spatially resolved molecular analysis of host response to medical device implantation using the 3D OrbiSIMS

The paper uses 3D OrbiSIMS to analyze metabolite signatures in tissue around implanted medical devices, linking them to pro- or anti-inflammatory immune responses.

Reduced local mechanical stimuli in spaceflight diminishes osteocyte lacunar morphometry and spatial heterogeneity in mouse cortical bone

This study shows that microgravity alters osteocyte lacunar shape and size in mouse cortical bone, with changes dependent on local mechanical loading and biological environment.

Augmented Transcutaneous Stimulation Using an Injectable Electrode

This paper presents an electroquasistatic model to improve transcutaneous power delivery to an injectable electrode by accounting for capacitive and resistive mechanisms.

Stimulation of the Dorsal Root Ganglion using an Injectrode

This study compares the effectiveness of an injectable polymer electrode (Injectrode) and a traditional metal electrode in stimulating dorsal root ganglion afferent fibers, finding similar activation thresholds and recruitment rates.

High-density spinal cord stimulation selectively activates lower urinary tract afferents

This study shows that high-density spinal cord stimulation in cats selectively activates lower urinary tract afferents through organized sensory pathways.

The effect of wrist posture on extrinsic finger muscle activity during single joint movements

This study quantifies how wrist posture affects extrinsic finger muscle EMG activity during movements, finding significant variations up to 70% and developing classifiers to predict wrist posture from EMG.

Approximating complex musculoskeletal biomechanics using multidimensional autogenerating polynomials

This paper introduces a method to efficiently compute musculoskeletal biomechanics using autogenerating polynomials, achieving fast and accurate results for real-time prosthetic control.