Epilepsy and premature mortality driven by inhibitory neuron dysfunction in a mouse model of SCN1A gain-of-function neurodevelopmental disorder
Sophie F. Hill, Zachary Rosenthal, Ethan M. Goldberg
This study develops a mouse model of SCN1A gain-of-function epilepsy and shows that inhibitory neuron dysfunction drives seizures and premature mortality.
bioRxiv · Aug 9, 2026 · PreprintNeuroscience