Correlative multiscale 3D imaging of mouse primary and metastatic tumors by sequential light sheet and confocal fluorescence microscopy
Jingtian Zheng, Yi-Chien Wu, Xiaoying Cai, Philana Phan, Meghna Gill, Ekrem Emrah Er, Zongmin Zhao, Zaijie J. Wang, Steve Seung-Young Lee
This paper develops a method to obtain correlative multiscale 3D images of mouse tumors using sequential light sheet and confocal fluorescence microscopy, enabling spatial analysis of immune responses and metastasis.
iScience · Feb 3, 2025Peer-reviewedCancer Biology