Author

Yi-Chien Wu

University of Illinois ChicagoORCID 0000-0002-2877-4476Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yi-Chien Wu1 paper · Agricultural Biotechnology Research Center, Academia Sinica

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Steve Seung-Young LeeiD· 2 shared Aditi UpadhyeiD· 1 shared Dylan SchwartziD· 1 shared Ekrem Emrah EriD· 1 shared Elie Abi KhaliliD· 1 shared Jalees RehmaniD· 1 shared Jingtian ZhengiD· 1 shared Meghna Gill· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Steve Seung-Young LeeORCID

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2 papers

Recent·Most cited

NicheProt: Cell-type-resolved proteomics of tissue compartments

Yi-Chien Wu, Dylan Schwartz, Elie Abi Khalil, Aditi Upadhye, Jalees Rehman, Seung Young Lee

NicheProt enables cell-type and microregion-resolved proteomic analysis by isolating specific cells from defined tissue compartments using 3D microscopy and photobleaching-mediated barcoding.

Science Advances · Jul 15, 2026Peer-reviewedSystems Biology

Correlative multiscale 3D imaging of mouse primary and metastatic tumors by sequential light sheet and confocal fluorescence microscopy

Jingtian Zheng, Yi-Chien Wu, Xiaoying Cai, Philana Phan, Meghna Gill, Ekrem Emrah Er, Zongmin Zhao, Zaijie J. Wang, Steve Seung-Young Lee

This paper develops a method to obtain correlative multiscale 3D images of mouse tumors using sequential light sheet and confocal fluorescence microscopy, enabling spatial analysis of immune responses and metastasis.

iScience · Feb 3, 2025Peer-reviewedCancer Biology