Establishment of murine in vitro blood-brain barrier models using immortalized cell lines: co-cultures of brain endothelial cells, astrocytes, and neurons
Fakhriedzwan Idris, Siti Hanna Muharram, Zainun Zaini, Suwarni Diah
This study establishes a murine in vitro BBB model using co-cultures of brain endothelial cells, astrocytes, and neurons, finding that triple co-culture best mimics in vivo BBB tightness.
bioRxiv · Oct 5, 2018 · PreprintCell Biology