A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice
Zakia Abdelhamed, Marshall Lukacs, Sandra Cindrić, Heymut Omran, Rolf W. Stottmann
This study identifies a hypomorphic Spag17 allele in mice that causes PCD-like phenotypes, revealing differential roles of SPAG17 in motile cilia development and hydrocephalus.
Disease Models & Mechanisms · Sep 8, 2020Peer-reviewedDevelopmental Biology