Total variation of quantitative phase map reveals cellular Young's modulus
Zhenghua Wang, Zebin Wang, Deyu Sun, Yin Li, Yujie Nie, Jialin Shi, Renjie Zhou, Lianqing Liu, Min Long, Yongliang Yang
This study uses quantitative phase microscopy to measure cellular Young's modulus in real time and finds that total variation of phase correlates with mechanical properties, revealing differences in stiffness between cell types in wound healing.
bioRxiv · Sep 8, 2025 · PreprintBiophysics