Molecular BiologybioRxivPreprint
Function expansion of antitumor transcriptional activator NFE2L1 by the original discovery of its non-transcription factor activity
Lu Qiu, Qiufang Yang, Peng Li…·Yanfeng Gao
This study discovers the non-transcription factor activity of NFE2L1 in cytoplasm, revealing its tumor suppressive role through Wnt/β-catenin signaling repression, independent of its transcriptional function.
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