LncRNA GAS6-AS1 contributes to 5-fluorouracil resistance in colorectal cancer
Zhonglin Zhu, Minghan Li, Junyong Weng, Shanbao Li, Tianan Guo, Yang Guo, Ye Xu
This study identifies GAS6-AS1 as a key regulator of 5-FU resistance in CRC by stabilizing MCM3 mRNA through PCBP1 recruitment, suggesting it as a therapeutic target.
bioRxiv · Jan 30, 2024 · PreprintMolecular Biology