Single-cell transcriptomics reveals immunosuppressive microenvironment and highlights stumor-promoting macrophage cells in Glioblastoma
Han Cheng, Yan Yan, Biao Zhang, Zhuolin Ma, Siwen Fu, Zhi Liang Ji, Ziji Zou, Qin Wang
This study uses single-cell transcriptomics to analyze GBM tumor microenvironment, identifying immunosuppressive macrophage subtypes and exhausted NK cells, suggesting therapeutic targets.
PLoS ONE · Apr 7, 2025Peer-reviewedCancer Biology