InstructPLM: Aligning Protein Language Models to Follow Protein Structure Instructions
Jiezhong Qiu, Junde Xu, Jie Hu, Hanqun Cao, Liya Hou, Zi-Jun Gao, Xinyi Zhou, Anni Li, Xiujuan Li, Bin Cui, Fei Yang, Shuang Peng, Ning Sun, Fangyu Wang, Aimin Pan, , Guangyong Chen
InstructPLM aligns a protein language model with structure instructions to generate diverse proteins, improving performance over existing models in sequence recovery and activity.
bioRxiv · Apr 17, 2024 · PreprintBioinformatics