Xiujuan Li

This paper uses AI to engineer a more stable and pH-tolerant glucoamylase variant, achieving higher starch conversion without acidification.

The paper structures and engineers deep-sea halophilic PET hydrolases to improve their salt tolerance and catalytic efficiency for industrial applications.

CASPE is a lightweight platform for site-directed protein engineering that improves the identification of beneficial mutations for thermostability and pH tolerance.

InstructPLM aligns a protein language model with structure instructions to generate diverse proteins, improving performance over existing models in sequence recovery and activity.