Microgravity Accelerates Skeletal Muscle Degeneration: Functional and Transcriptomic Insights from a Muscle Lab-on-Chip Model Onboard the ISS.
Maddalena Parafati, Zon Thwin, Legrand K. Malany, Paul M. Coen, Siobhan Malany
This study uses a muscle lab-on-chip model on the ISS to show microgravity accelerates muscle degeneration, with younger muscles showing increased aging gene expression under microgravity when stimulated.
Stem Cell Reports · Jun 26, 2025Peer-reviewedCell Biology