Author

Carsten Skarke

University of PennsylvaniaORCID 0000-0001-5145-3681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Amita SehgaliD· 1 shared Antonijo Mrčela· 1 shared Bahram NamjouiD· 1 shared Benjamin F. VoightiD· 1 shared Binglan LiiD· 1 shared Blair D. SullivaniD· 1 shared Casey S. GreeneiD· 1 shared Chun SuiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Amita SehgalORCID

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2 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedNov 1, 2024

Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms

Jessica E. Schwarz, Antonijo Mrčela, Nicholas F. Lahens…·Amita Sehgal

This study shows that age-related blood-borne factors alter circadian gene expression in cultured fibroblasts, affecting oxidative phosphorylation and cholesterol biosynthesis pathways.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsNature CommunicationsPeer-reviewedSep 9, 2023

Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms

Milton Pividori, Sumei Lu, Binglan Li…·Casey S. Greene

This paper introduces PhenoPLIER, a method that maps gene-trait and drug associations into gene modules to reveal disease mechanisms and drug targets.

22 citations

humanbulk RNA-seq

𝕏 PostBluesky