Genetic & Genomic MedicineJournal of Medical VirologyPeer-reviewed
Disentangling the common genetic architecture and causality of rheumatoid arthritis and systemic lupus erythematosus with COVID-19 outcomes: genome-wide cross trait analysis and bi-directional Mendelian randomization study
Minhao Yao, Xin Huang, Yunshan Guo…·Zhonghua Liu
The paper identifies shared genetic loci between COVID-19 outcomes and rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) using cross-trait analysis and Mendelian randomization, finding increased RA genetic risk correlates with higher COVID-19 hospitalization risk.
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