Author

Lisa J. Oyston

The University of SydneyORCID 0000-0001-5271-3537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Carol Dobson‐StoneiD· 2 shared John B. KwokiD· 2 shared Lauren Fitzpatrick· 2 shared Lauren M. Boccanfuso· 2 shared Marianne Hallupp· 2 shared Johnny Zhang· 1 shared Stephanie Ubiparipovic· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 20 mutual co-author links

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2 shared papersGenetics

Carol Dobson‐StoneORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintJun 2, 2022

TDP-43 subcellular mislocalisation is correlated with loss of optineurin binding for frontotemporal dementia and amyotrophic lateral sclerosis associated TBK1 missense variants

Lisa J. Oyston, Lauren M. Boccanfuso, Lauren Fitzpatrick…·Carol Dobson‐Stone

The paper investigates how TBK1 missense variants affect TDP-43 mislocalization and OPTN binding in FTD and ALS, finding that loss of OPTN binding is more critical than kinase activity.

DOI 10.1101/2022.06.02.494603

humanexperimental assay

Molecular BiologyScientific ReportsPeer-reviewedJul 21, 2021

Rapid and automated quantification of TDP-43 and FUS mislocalisation for screening of frontotemporal dementia and amyotrophic lateral sclerosis gene variants

Lisa J. Oyston, Stephanie Ubiparipovic, Lauren Fitzpatrick…·Carol Dobson‐Stone

This paper develops an automated method to quantify TDP-43 and FUS mislocalization in human cell lines to assess the pathogenicity of FTD and ALS gene variants.

6 citations

humanproteomics