Author
Technical University of DenmarkORCID 0000-0001-5280-1107Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Felix Teufel, Jeppe Hallgren, Henrik Nielsen…·Ole Winther
DeepTMHMM2 predicts transmembrane protein topology and subcellular location, including re-entrant regions and interfacial helices, and identifies localization across 17 membranes.
Andrew Anand Brown, Juan J. Fernandez-Tajes, Mun‐Gwan Hong…·Ulrik Plesner Jacobsen
The paper identifies shared genetic regulation across mRNA, proteins, and metabolites in blood, revealing networks and mediators of GWAS variants.
Jeppe Hallgren, Konstantinos D. Tsirigos, Mads D. Pedersen…·Ole Winther
Combining an ESM-1b encoder with a conditional random field decoder, DeepTMHMM classifies alpha-helical and beta-barrel transmembrane proteins and their topology, outperforming most compared tools, including on signal-peptide cleavage sites.
Felix Teufel, José Juan Almagro Armenteros, Alexander Rosenberg Johansen…·Henrik Nielsen
SignalP 6.0 predicts all five types of signal peptides with improved accuracy and applies to metagenomic data.