Author

Rachel M. Pepin

Mayo ClinicORCID 0000-0001-5303-8860Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:multiome· 1

Frequent Co-Authors

Mariah K NovakiD· 2 shared Qiuying LiuiD· 2 shared Wenqian HuiD· 2 shared Katharine R. MaschhoffiD· 1 shared Shaojie ZhangiD· 1 shared Taylor Eich· 1 shared Xiaoli Chen· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

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2 shared papersMolecular Biology

Mariah K NovakORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 14, 2022

A congenital hydrocephalus causing mutation in Trim71 results in stem cell differentiation defects through inhibiting Lsd1 mRNA translation

Qiuying Liu, Mariah K Novak, Rachel M. Pepin…·Wenqian Hu

This study identifies a mutation in Trim71 that causes congenital hydrocephalus by impairing stem cell differentiation through repression of Lsd1 mRNA translation.

DOI 10.1101/2022.04.14.488304

mousebulk RNA-seq

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Molecular BiologyeLifePeer-reviewedOct 1, 2021

microRNA-mediated regulation of microRNA machinery controls cell fate decisions

Qiuying Liu, Mariah K Novak, Rachel M. Pepin…·Wenqian Hu

The paper shows that microRNA-182/microRNA-183 repress Ago2 to maintain pluripotency in mESCs, revealing a regulatory circuit involving microRNA machinery.

25 citations

mousemultiome

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