Author

Jeffrey L Hansen

Washington University in St. LouisORCID 0000-0001-5343-9066Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Barak A. CoheniD· 2 shared Kaiser LoelliD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersGenomics

Barak A. CohenORCID

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2 papers

Recent·Most cited

GenomicsGenome biologyPeer-reviewedOct 17, 2022

A quantitative metric of pioneer activity reveals that HNF4A has stronger in vivo pioneer activity than FOXA1

Jeffrey L Hansen, Barak A. Cohen

The paper introduces a quantitative metric to measure pioneer activity of transcription factors and finds HNF4A has stronger in vivo pioneer activity than FOXA1.

32 citations

humanATAC-seq

𝕏 PostBluesky

GenomicseLifePeer-reviewedJan 5, 2022

A Test of the Pioneer Factor Hypothesis

Jeffrey L Hansen, Kaiser Loell, Barak A. Cohen

The paper tests the Pioneer Factor Hypothesis by expressing FoxA1 and Hnf4a in K562 cells, finding no functional distinction between the two TFs and proposing an alternative model based on binding affinity and genomic context.

62 citationstop 3%

humanbulk RNA-seq

𝕏 PostBluesky