Molecular BiologybioRxivPreprint
Clean-PIE: a novel strategy for efficiently constructing precise circRNA with thoroughly minimized immunogenicity to direct potent and durable protein expression
Zonghao Qiu, Qiangbo Hou, Yang Zhao…·Chijian Zuo
Clean-PIE generates high-purity, low-immunogenic circRNAs that enable durable protein expression in vitro and in vivo.
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