ImmunologybioRxivPreprint
Constraints and tunability of antigen-agnostic memory durability
Shubham Tripathi, Can Liu, William W. Lau…·John S. Tsang
This study develops mathematical models and simulations to show that antigen-agnostic memory durability is constrained by immune cell turnover, cytokine dependence, and epigenetic state transmission, and can be tuned via cytokine-mediated feedback.