Author

Lyle L. Nelson

Massachusetts Institute of TechnologyORCID 0000-0001-5546-0387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:phylogenetics / evolution· 1 Approach:simulation· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Erik TamreiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

1 paper

Recent·Most cited

Evolutionary BiologybioRxivPreprintMay 26, 2026

Variability and scale-dependence in molecular evolution rate impacts interpretation of eukaryotic evolutionary histories

Erik Tamre, Lyle L. Nelson

The paper shows that molecular evolution rates vary with timescale, affecting evolutionary history inferences, and is analogous to the Sadler effect in geology.

DOI 10.64898/2026.05.25.724440

DNA methylationwhole-genome sequencing

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