BioinformaticsVirus EvolutionPeer-reviewed
Large-scale analysis of SARS-CoV-2 synonymous mutations reveals the adaptation to the human codon usage during the virus evolution
Daniele Ramazzotti, Fabrizio Angaroni, Davide Maspero…·Rocco Piazza
The paper analyzes SARS-CoV-2 synonymous mutations across 400,000 samples, showing that mutations increasing codon similarity to human codons tend to persist, suggesting adaptation to human host codon usage.
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