Host-encoded DNA methyltransferases modify the epigenome and host tropism of invading phages
Michiko Takahashi, Satoshi Hiraoka, Yuki Matsumoto, Rikako Shibagaki, Takako Ujihara, Hiromichi Maeda, Satoru Seo, Keizo Nagasaki, Hiroaki Takeuchi, Shigenobu Matsuzaki
The paper shows adapted phages share methylated motifs with their most recent host, indicating epigenetic changes influence host tropism.
iScience · Mar 22, 2025Peer-reviewedMicrobiology