Samir Kumar Patra

AKNA drives neural stem cell fate transition through differential localization and coordinating the modulation of chromatin from H3K27me3 to H3K27ac

The paper shows AKNA regulates neural stem cell fate by modulating chromatin states through interactions with KDM6B and signaling pathways.

Screening and identification of gene expression in large cohorts of clinical lung cancer samples unveils the major involvement of EZH2 and SOX2

The paper identifies EZH2 and SOX2 as key genes in LUAD through differential expression analysis and pathway enrichment, suggesting EZH2 as a potential therapeutic target.

Modulation of H3K4 trimethylation by KDM5A and MLLs impacts metabolic adaptability in prostate and cervical cancer cells

This study shows that KDM5A and MLLs modulate metabolic adaptability in prostate and cervical cancer cells by regulating H3K4me3 levels on metabolic gene promoters.

Physical association of functionally antagonistic enzymes: KDM5A interacts with MLLs to regulate gene expression in a promoter specific manner facilitating EMT and pluripotency.

The paper shows KDM5A interacts with MLLs to regulate gene expression in a promoter-specific manner, promoting EMT and pluripotency through distinct epigenetic mechanisms.