BioinformaticsbioRxivPreprint
In silico screening of TMPRSS2 SNPs that affect its binding with SARS-CoV2 spike protein and directly involved in the interaction affinity changes
Fatma Nouira, Manel Hamdi, Alaeddine Redissi…·Amor Mosbah
The paper identifies 17 TMPRSS2 SNPs affecting binding with SARS-CoV2 spike protein, with four increasing and two decreasing interaction affinity, linked to population-specific genetic factors.
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