Author

James Utley

ORCID 0000-0001-5645-726XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Daniel BriggsiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintNov 16, 2025

Age-Associated Expression of DIMT1 (Dimethyladenosine Transferase) in Human Mesenchymal Stromal Cells: A Candidate for Multi-Gene Aging Signatures

James Utley

This study finds a positive correlation between DIMT1 expression and donor age in human mesenchymal stromal cells, suggesting its potential role in multi-gene aging signatures.

DOI 10.1101/2025.11.16.25340333

humanbulk RNA-seq

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Cell BiologybioRxivPreprintMay 16, 2024

Age-Related KLHL22 Expression in Human MSCs and Regenerative Implications

James Utley, Daniel Briggs

This study identifies KLHL22 as a gene with age-related expression in hMSCs, suggesting its potential as a marker for selecting more effective cells for regenerative therapies.

DOI 10.1101/2024.05.16.594601

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintMay 11, 2024

FOSL2 Gene Expression Declines with Age in Bone Marrow-derived MSCs

James Utley, Daniel Briggs

This study shows FOSL2 gene expression decreases with age in human bone marrow-derived mesenchymal stromal cells, suggesting its role in aging and regenerative capacity decline.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky