Genetic & Genomic MedicinemedRxivPreprint
PA-FGRS is a novel estimator of pedigree-based genetic liability that complements genotype-based inferences into the genetic architecture of major depressive disorder
Morten Dybdahl Krebs, Kajsa-Lotta Georgii Hellberg, Mischa Lundberg…·Andrew Joseph Schork
The paper introduces PA-FGRS, a method to estimate genetic liability from family records, and shows it improves MDD classification and GWAS power when combined with genotypes.
8 citations