ImmunologybioRxivPreprint
TL1A-activated T cells remodel the rectal mucosa in Crohn's disease patients with perianal fistulizing disease
Victòria Gudiño, Jae Won Cho, Berta Caballol…·Azucena Salas
The paper identifies TL1A-driven cellular and transcriptomic changes in rectal mucosa of Crohn's disease patients with perianal fistulizing disease, revealing a novel TL1A-LT1{beta}2/IL-22 axis independent of TNF signaling.