Genetic & Genomic MedicinemedRxivPreprint
Interplay between mosaic chromosomal alterations and polygenic risk score increases risk of non-small cell lung cancer
Na Qin, Congcong Chen, Yang Liu…·Zhibin Hu
The paper examines the association between mosaic chromosomal alterations and polygenic risk scores in NSCLC risk, finding that mosaic loss increases risk, especially in high genetic risk individuals.
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