Juncheng Dai

Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers

The paper develops and validates multi-ancestry polygenic risk scores for LUAD in East Asian never-smokers, showing improved risk prediction compared to East Asian-only models.

Interplay between mosaic chromosomal alterations and polygenic risk score increases risk of non-small cell lung cancer

The paper examines the association between mosaic chromosomal alterations and polygenic risk scores in NSCLC risk, finding that mosaic loss increases risk, especially in high genetic risk individuals.

RNAIndel: a machine-learning framework for discovery of somatic coding indels using tumor RNA-Seq data

RNAIndel identifies somatic coding indels in tumor RNA-Seq data with high sensitivity and low false positives, outperforming existing methods.

Meiosis related cancer-testis genes correlate with tumor aneuploidy and immune infiltration in 21 cancer types

The paper investigates the correlation between meiosis-related cancer-testis genes, tumor aneuploidy, and immune infiltration across 21 cancer types using multi-omics data.