Author

Lusiné Nazaretyan

Berlin Institute of Health at Charité - Universitätsmedizin BerlinORCID 0000-0001-5820-4143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Organism:human· 2 Research Focus:variant effect prediction· 2 Organism:bacteria (other)· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Martin KircheriD· 2 shared Alexander Martin GelleriD· 1 shared Asaf LevyiD· 1 shared Avital Akerman-AradiD· 1 shared Cristina BeziD· 1 shared Fei Chen· 1 shared Max SchubachiD· 1 shared Ori SegeviD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioinformatics

Martin KircherORCID

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3 papers

Recent·Most cited

BioinformaticsGenome MedicinePeer-reviewedAug 4, 2025

varCADD: large sets of standing genetic variation enable genome-wide pathogenicity prediction

Lusiné Nazaretyan, Philipp Rentzsch, Martin Kircher

The paper introduces varCADD, a method using standing genetic variation to predict variant pathogenicity, showing improved accuracy over existing tools in certain genomic regions.

8 citationstop 4%

humanwhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivPreprintJul 19, 2025

The Genetic Basis of Bacterial Adaptation to Hosts

Ori Segev, Alexander Martin Geller, Cristina Bez…·Asaf Levy

This study identifies host-associated bacterial genes and functions using comparative genomics, revealing new roles in host-microbe interactions and microbial evolution.

DOI 10.1101/2025.07.19.665706

bacteria (other)whole-genome sequencing

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BioinformaticsbioRxivPreprintMar 14, 2022

The Regulatory Mendelian Mutation score for GRCh38

Lusiné Nazaretyan, Martin Kircher, Max Schubach

The paper updates the Regulatory Mendelian Mutation score for GRCh38 and provides a website and API for variant scoring.

1 citation

humanwhole-genome sequencing

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