Mateusz Bujko

This paper identifies four genomic clusters in skull base chordoma based on copy-number events, linking them to transcriptional programs and therapeutic implications.

The paper identifies acromegaly-related PIT-1/SF-1 positive pituitary tumors as a subtype of PIT-1 lineage tumors through transcriptomic analysis, showing they differ from gonadotroph tumors despite SF-1 activity.

The paper identifies copy number alterations in highly aneuploid tumors using genome-wide methods and highlights the bias from improper normal ploidy level setting in LPWGS and methylation arrays.