Balasubramanian Narasimhan

The paper investigates the role of Wnt signaling in cochlear development, showing that Wnt proteins from both epithelial and mesenchymal compartments guide cochlear outgrowth and hair cell polarization, with redundancy across compartments.

CuGen is a GPU-accelerated framework for large-scale genomics that enables efficient GWAS and fine-mapping with robust confounding control.

The paper develops efficient solvers for large-scale regularized regressions on genetic data, reducing memory usage and improving computational speed.

The paper uses DeGAs to identify genetic components across 2,138 phenotypes in the UK Biobank, revealing novel adipocyte biology through variant and gene contributions to obesity-related traits.