Sleep deprivation exhibits age-dependent effect on infra-slow global brain activity
Yibing Yang, Weiwei Zhao, Yutong Mao, Tianxin Mao, Yao Deng, Yifan Yang, Hengyi Rao, Xiao Liu
This study shows sleep deprivation increases global brain activity and its link to CSF flow, but this effect weakens with age, potentially increasing dementia risk.
bioRxiv · Sep 12, 2025 · PreprintNeuroscience