Author

Prabhat Totoo

European Bioinformatics InstituteORCID 0000-0001-5923-4467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Edward P. O’BrieniD· 1 shared Hyebin SongiD· 1 shared Ian M. SitarikiD· 1 shared James D. StephensoniD· 1 shared Maria F Anglero Mendez· 1 shared Quyen V. VuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Edward P. O’BrienORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintApr 20, 2026

Natively entangled proteins are linked to human disease and pathogenic mutations likely due to a greater misfolding propensity

Maria F Anglero Mendez, Ian M. Sitarik, Quyen V. Vu…·Edward P. O’Brien

The paper investigates whether proteins with native entanglements are more prone to misfolding and associated with disease, finding significant statistical associations.

DOI 10.64898/2026.04.15.718104

humanprotein structure

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