BioengineeringInternational Journal of Biological MacromoleculesPeer-reviewed
A Combinatorial Strategy for HRV 3C Protease Engineering to Achieve the N-terminal Free Cleavage
Meng Mei, Xian Fan, Yu Zhou…·Yi Li
This paper develops a combinatorial strategy to engineer HRV 3C protease for N-terminal free cleavage by expanding P1 specificity through structure-guided library design and high-throughput screening.