Author
NIHR Southampton Respiratory Biomedical Research UnitORCID 0000-0001-6039-5612Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Cornelia Blume, Claire L. Jackson, Cosma Mirella Spalluto…·Vito Mennella
The paper identifies a novel short ACE2 isoform expressed in respiratory epithelia that is upregulated by interferon and RNA virus infection but not SARS-CoV-2, and shows reduced SARS-CoV-2 binding affinity.
James P R Schofield, Fabio Strazzeri, Jeannette Bigler…·Paul J Skipp
The paper uses a discrete Morse theory clustering algorithm on a TDA network of gene expression data to identify nine molecular phenotypes associated with asthma and glucocorticoid receptor signaling differences.
Alen Faiz, Stelios P Pavlidis, C-H.S. Kuo…·Maarten van den Berge
The paper identifies a corticosteroid-sensitive gene cluster in COPD patients using asthma-derived transcriptomic signatures and links it to mast cell numbers and lung function improvement.