Author

Pinyuan Tian

Wellcome Centre for Cell-Matrix ResearchORCID 0000-0001-6080-5378Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Bruno Estebe· 1 shared Christelle ArrondeliD· 1 shared Corinne AntignaciD· 1 shared Géraldine MolletiD· 1 shared Guillaume DorvaliD· 1 shared Hassan SaeiiD· 1 shared Julie Haure· 1 shared Mahsa Esmailpour· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Bruno Estebe

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1 paper

Recent·Most cited

Therapeutic splice modulation of COL4A5 reinstates collagen IV assembly in an organoid model of X-linked Alport syndrome

Hassan Saei, Bruno Estebe, Nicolas Goudin, Mahsa Esmailpour, Julie Haure, Olivier Gribouval, Christelle Arrondel, Vincent Morinière, Pinyuan Tian, Rachel Lennon, Corinne Antignac, Géraldine Mollet, Guillaume Dorval

The paper demonstrates that ASO treatment restores 5(IV) collagen in XLAS patient-derived kidney organoids, supporting therapeutic potential for splicing modulation.

JCI Insight · Dec 18, 2025Peer-reviewedGenetics