Author
Manchester Academic Health Science CentreORCID 0000-0001-6400-0227Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Allison D. Henry, Annica L. Alwine, Matthew J. Niederhuber…·Erin J. Plosa
This study shows that integrin α3β1 is essential for alveolar-capillary barrier formation by regulating epithelial differentiation during lung development.
Rebecca Preston, Anna Hoyle, Alana Stevenson Harris…·Rachel Lennon
This study quantifies age-related changes in kidney extracellular matrix turnover and identifies structural and functional alterations linked to fibrosis.
Amber Emmett, Xiaoguang Xu, Xiao Jiang…·Maciej Tomaszewski
The paper identifies 508 CKD-associated genetic loci, prioritizes 651 kidney genes, and highlights novel CKD genes like CA12 with functional consequences.
Hassan Saei, Bruno Estebe, Nicolas Goudin…·Guillaume Dorval
The paper demonstrates that ASO treatment restores 5(IV) collagen in XLAS patient-derived kidney organoids, supporting therapeutic potential for splicing modulation.
Céline Grenier, I‐Hsuan Lin, Dorien J.M. Peters…·Richard William Naylor
This study shows that integrin alpha1 beta1 promotes fibrosis in a mouse model of ADPKD, as its deletion reduces kidney volume, cyst size, and fibrotic markers.
Oliver J. Brand, Sara Kirkham, Christopher P. Jagger…·Alexander Eckersley
This study identifies persistent structural and compositional changes in lung basement membranes in mice recovering from influenza infection and links these changes to aging-related lung complications.
E. G. Williams, Maryline Fresquet, Gema Bolás…·Rachel Lennon
This study evaluates AAV9 transduction efficiency in Alport syndrome podocytes, finding enhanced transduction in Alport podocytes both ex vivo and in vivo.
Sandhya Srinivasan, Willam Ramos-Lewis, Mychel Morais…·David R. Sherwood
The paper constructs a collagen IV fluorophore knock-in toolkit in C. elegans to study -chain diversity and basement membrane defects in collagen IV mutants.