Maria E. Plataki

This study examines the effects of working memory training on cognitive flexibility, dendritic spine density, and long-term potentiation in female mice, finding no differences in cognitive flexibility but increased spine density and LTP in the hippocampus.

This study shows that long-term synaptic depression triggers local autophagic vesicle biogenesis in dendrites, which is essential for synaptic remodeling and cognitive flexibility.