Fangfang Yan

This paper identifies BMP signaling as a driver of heterotopic ossification by promoting ciliogenesis and establishing a sensitized signaling hub that facilitates osteochondrogenic differentiation.

This study uses single-cell multi-omics to map regulatory programs during mouse secondary palate development, identifying key transcription factors involved in anterior and posterior palatal mesenchymal differentiation.

deCS improves cell type annotation in scRNA-seq data by using a comprehensive human cell type reference atlas, enhancing accuracy and reducing computation time.

EmptyNN improves scRNA-seq quality by removing cell-free droplets and recovering lost cells using positive-unlabeled learning, achieving high AUROC scores and outperforming existing methods.

DrivAER identifies driving transcriptional programs in scRNA-seq data by scoring gene sets for their relevance to pseudotemporal ordering or disease status.