Author

Andrés Arguedas

Universidad de Costa RicaORCID 0000-0001-6299-052XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro LealiD· 1 shared Gabriel Jiménez-Huezo· 1 shared Luis Bermúdez-GuzmániD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperMolecular Biology

Alejandro LealORCID

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1 paper

Recent·Most cited

Molecular BiologyPLoS ONEPeer-reviewedDec 17, 2020

Mutational Survivorship Bias: The case of PNKP

Luis Bermúdez-Guzmán, Gabriel Jiménez-Huezo, Andrés Arguedas, Alejandro Leal

The paper identifies a survivorship bias in mutational analysis of PNKP, showing the phosphatase domain is less mutation-tolerant despite being less associated with disease.

10 citations

humanprotein sequence

𝕏 PostBluesky