Author

Keijun Kakihara

Academia SinicaORCID 0000-0001-6331-1330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akinori KideraiD· 1 shared Gai Ando· 1 shared Hidenori FukuokaiD· 1 shared Kei MoritsuguiD· 1 shared Masayuki KomadaiD· 1 shared Shozo Yamada· 1 shared Toshiaki FukushimaiD· 1 shared Yasutaka TsujimotoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Akinori KideraORCID

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1 paper

Recent·Most cited

Molecular bases for USP48 cis-activity regulation and hyperactivation by Cushing's disease-associated mutations

Gai Ando, Yasutaka Tsujimoto, Kei Moritsugu, Keijun Kakihara, Akinori Kidera, Shozo Yamada, Masayuki Komada, Hidenori Fukuoka, Toshiaki Fukushima

This study identifies molecular mechanisms by which USP48 mutations in Cushing's disease enhance enzyme activity through structural changes in the catalytic domain and C-terminal region.

bioRxiv · Dec 28, 2025 · PreprintMolecular Biology