Systems BiologyPLoS Computational BiologyPeer-reviewed
An extension of the Walsh-Hadamard transform to calculate and model epistasis in genetic landscapes of arbitrary shape and complexity
André J. Faure, Ben Lehner, Verónica Miró Pina…·Donate Weghorn
This paper extends the Walsh-Hadamard transform to model epistasis in genetic landscapes with multiple alleles per position, enabling analysis of pairwise and higher-order interactions in simulated and empirical data.
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